1.1 Selection of the location and environment of the clean laboratory
Clean laboratories should comply with the design requirements of cleanliness levels in terms of location selection. They should choose areas and sections with low atmospheric dust concentration and good natural environment, and should be far away from places with fallen leaves and air odors, such as riversides, canteens, etc. Power area, etc.), and try to avoid areas disturbed by vibration or noise. When choosing the location, terrain, and environment around the laboratory, it is necessary to analyze and weigh the allowable environmental vibration values of precision equipment, precision instruments, and meters.
1.2 Standards for wall enclosure of clean laboratory
The pollution sources of clean laboratories are generally dust, bacteria, dust particles and microorganisms in the atmosphere, dust generated by experimenters, and dust generated during experimental equipment and experimental operations. Therefore, the quality of building envelope and construction methods are of great significance to maintaining and improving the standards of clean laboratories. The outer protective structure of the clean laboratory, such as doors and windows, wall panels, ceiling panels, high-efficiency filters, electrical lamps, etc., must fully consider the requirements of good heat preservation, heat insulation, fire resistance, moisture resistance, and airtight performance, so as not to produce dust, It has no cracks, can be scrubbed, and is resistant to moisture. The seams are flush and sealed, and the seam strips are straight and small. The ground strives to be abrasion-resistant, impact-resistant, fire-resistant, and corrosion-resistant, not easy to generate static electricity, and not easy to adhere to dust particles on the surface.
1.3 The overall layout design of the clean laboratory
The plane and space design of the clean laboratory should be divided into zones for the clean experimental area and personnel purification, equipment and material purification and other auxiliary rooms. At the same time, the comprehensive coordination effect of various technical facilities such as experimental operation, process equipment installation and maintenance, air flow organization type, pipeline layout, and purification air conditioning system should be considered. The arrangement of various fixed technical facilities (such as air supply outlets, luminaires, return air outlets, various pipelines, etc.) in the laboratory should first consider the requirements of the clean air conditioning system.
2.Air purification and regulation system in clean laboratory
In general, the control temperature of the clean area of level 5 and 6 is 20℃～24℃, and the relative humidity is 45%～65%; the control temperature of the clean area of grade 7 and greater than 7 is 18℃～28℃, and the relative humidity is 50 %～65%. When there are no special requirements for clean room temperature and humidity, the temperature should be controlled at 18℃～26℃, and the relative humidity should be controlled at 45%～65%. In addition, the air flow rate, air supply volume and fresh air volume must meet the requirements of the laboratory facilities and personnel of the clean room. Because the purification laboratory is a relatively independent and enclosed space, while maintaining temperature, humidity, and air flow rate, measures must be taken to compensate for indoor exhaust air and the amount of fresh air required to maintain indoor positive pressure (or negative pressure) values. With the continuous improvement of cleanliness requirements, it is also necessary to use ultra-high-efficiency filters, so the air handling units must be equipped with at least primary, medium-efficiency, and sub-high-efficiency filter systems, so that the strength of the unit is higher, and the air The pressure head of the blower of the processing unit will be larger, and for the biological clean laboratory, the bacterial content is also one of the main control parameters. Generally, a filter should be added to the air purification treatment method, which can not only effectively filter the dust in the air, but also It can also block the spread and spread of bacteria and viruses in air conditioning systems, especially high-efficiency filters. The capture efficiency of viruses and bacteria floating in the atmosphere can actually reach 100%. Filters can also be used to effectively prevent bacteria from growing in the filter. Device. Such as filters containing the antibacterial agent INTESEPT, titanium dioxide filters, etc., the filters should be replaced regularly.